Abstract Introduction To establish the preclinical safety and equivalency of ophthalmic viscosurgical devices (OVDs) comprised of bacterially sourced sodium hyaluronate (HA) to animal sourced HA using pyrogenicity and aqueous exchange models in rabbits and a novel mini-pig model to evaluate corneal endothelial cell protection in vivo. Methods HEALON OVD and HEALON5 OVD containing anim... https://jalyttlers.shop/product-category/newtons-cradle/