Abstract Background We examined whether impaired renal function causes thickening of the aortic valve leaflets in hyperlipidemic apoE-knockout (apoE-/-) mice. and whether the putative effect on the aortic valves could be prevented by inhibiting the angiotensin-converting enzyme (ACE) with enalapril. Methods Thickening of the aortic valve leaflets in apoE-/- mice was induced by produci... https://www.greenresourcesredux.com/product-category/low-density/